CRCHUS Research

An approach combining fundamental, clinical, epidemiological, and evaluative research is the distinguishing feature of the CHUS’ research centre. Some 220 top researchers and their teams devote their efforts to six research axes, which address major health concerns: Cancer: biology, prognosis, and diagnosis | Diabetes, obesity, and cardiovascular complications | Health: populations, organization, practices | Inflammation – Pain | Medical imagery | Mother and child. The CHUS’ research centre provides ground-breaking scientific and technological leadership nationally and internationally. Its breakthroughs in research invariably result in improved care and services.

CRCHU de Quebec

The Research Center is part of the CHU de Québec-Université Laval and is affiliated to Université Laval .

The Research Center rounds up all research activities at the CHUL, Hôtel-Dieu de Québec, l’Enfant-Jésus, Saint-François d’Assise and Saint-Sacrement hospitals.

Study Team


Dr. Louis Valiquette

Professor and chair of the Department of Medical Microbiology and Infectious Diseases at the Faculty of Medicine and Health Sciences, Université de Sherbrooke, Sherbrooke, Québec.

Dr. Valiquette is a professor and chair of the Department of Medical Microbiology and Infectious Diseases at the Faculty of Medicine and Health Sciences, Université de Sherbrooke. He has been involved in CANVAS as the Sherbrooke site lead investigator since the beginning of this project. His other research interests include antimicrobial stewardship with a focus on the development and validation of clinical decision support systems and Clostridium difficile infections. With his team, he has developed an expert system (called APSS) to optimize antimicrobial usage that has been associated with a substantial decrease in antimicrobial consumption, length of stay and savings since its installation in his center.

Study Team


Gaston De Serres, M.D

Axe Maladies infectieuses et immunitaires, Estimauville
Professeur titulaire
Département de médecine sociale et préventive
Faculté de médecine, Université Laval

Dr. Gaston De Serres is a physician-epidemiologist the National Institute of Public Health, and a regular researcher in the Infectious and Immunity Diseases Axis at the CHU de Québec-Université Laval Research Center. He is a full professor of epidemiology in the Department of Social and Preventive Medicine at Laval University where he has been teaching since 1997. He is head physician of the scientific group in immunization (GSI) of the National Institute of Public Health and an active member of the Quebec Immunization Committee (CIQ).


Dr. De Serres works in the field of infectious disease control and prevention, with a focus on vaccine-preventable diseases and respiratory infections. His research focuses on the epidemiology of vaccine-preventable diseases, the investigation of vaccine side effects and the effectiveness of vaccines used in routine immunization programs, and in particular the effectiveness of the influenza vaccine and COVID-19.

Site Coordinator

Cynthia Grenier Pharmacologue, MSc

Cynthia is working at Centre de Recherche du CHUS since 2010 in the microbiology and infectious diseases research team.

She is working on many epidemiological studies including those on pneumonia, flu and the annual flu vaccine safety surveillance. She is also in charge of COVID19 vaccine safety surveillance.

(819) 820-6855

Research Coordinator

Sandrine Hegg, Ph.D

Sandrine Hegg has a PhD in Kinesiology with a specialization in Exercise Physiology.

She has been in Quebec for 16 years and resumed her university studies upon her arrival. She has been working as a research coordinator at the Centre de Recherche du CHU de Québec-Université Laval for more than 5 years, first in nursing science, then for doctors in the emergency room (Axis in population health and optimal health practices). Sandrine joined the Infectious and Immunity Diseases Axis in 2020. She also teaches at Laval University and the University of Quebec in Rimouski since 2013.